Comparative Pharmacokinetics of Intramuscular Ceftriaxone Co-Administered with Acetaminophen in Healthy and Infected Sokoto Red Goats
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چکیده
منابع مشابه
Pharmacokinetics of ceftriaxone in buffalo calves (Bubalus bubalis) following intravenous and intramuscular administration
Pharmacokinetics of ceftriaxone was studied in buffalo calves (Bubalus bubalis) after single intravenousand intramuscular administration of 10 mg/kg body weight. The drug concentrations in plasma samples weremeasured by high performance liquid chromatography with UV detection. Following intravenousadministration, the drug was rapidly distributed (Cpo: 106.5 ± 9.64 μg/ml; t1/2α: 0.09 ± 0.01 h; V...
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Kumar, S. 130 INTRODUCTION Ceftriaxone is effective in a variety of infections including meningitis, septicemia, pyoderma, colibacillosis, surgical prophylaxis and infections of the urinary tract, respiratory tract, wounds, soft tissues and joints (1). It is characterized by its excellent activity against Gram-negative pathogens including Salmonella, Shigella, Proteus, Klebsiella, Enterobacter,...
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This study was conducted to identify whether or not a pharmacokinetic interaction existed when azithromycin and ceftriaxone were administered concurrently. This randomized, open-label, three-way crossover study in 12 healthy volunteers characterized the plasma pharmacokinetic parameter profiles of both drugs, as well as the white blood cell uptake and exposure to azithromycin, when the drugs we...
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The comparative pharmacokinetic profile of cefquinome was studied in sheep and goats following repeated intramuscular (IM) administrations of 2 mg/kg body weight. Cefquinome concentrations in serum were determined by microbiological assay technique using Micrococcus luteus (ATCC 9341) as test organism. Following intramuscular injection of cefquinome in sheep and goats, the disposition curves we...
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ژورنال
عنوان ژورنال: International Journal of Pharmacology
سال: 2011
ISSN: 1811-7775
DOI: 10.3923/ijp.2011.623.628